Ms. De Los Reyes has handled significant matters, including:
- representing a business process outsourcing company in filing several cybercrime cases against its employees;
- assisting a PEZA-registered company in initiating voluntary liquidation proceedings;
- assisting a financial institution in transferring the titles of its properties in Visayas and Mindanao as payment for its subscription to another corporation;
- assisting a manufacturing company in the purchase of PhP200-million property;
- representing shipping companies in challenging the constitutionality of certain local ordinances and resolving legal disputes over their tenurial agreements with the DENR;
- representing a shipyard association in lobbying against environmental issues related to a proposed local reclamation project; and
- representing a politician in several graft and corruption, malversation, and bribery cases before the Sandiganbayan.
Ms. De Los Reyes represented the Philippines in the 2019 Stetson International Environmental Moot Court Competition in Florida, USA (via videoconference).
Ms. De Los Reyes was admitted to the Philippine Bar in 2022 and is a member of the Cebu City Chapter of the Integrated Bar of the Philippines.